科研實證

Exosome

Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases
間質幹細胞衍生的外泌體作為肝病的新治療策略

Mesenchymal stem cell-derived exosomes for clinical use
間質幹細胞衍生的外泌體用於臨床

Advances in mesenchymal stem cell exosomes: a review
綜述間質幹細胞外泌體的進展

Mesenchymal stem cell derived‑exosomes: a modern approach in translational medicine
間質幹細胞衍生的外泌體:轉化醫學的現代方法

hbFGF

A Complex Role for FGF-2 in Self-renewal, Survival, and Adhesion of Human Embryonic Stem Cells FGF-2在人類胚胎幹細胞的自我更新,存活和粘附中起著複雜的作用。

A Crucial Role of Fibroblast Growth Factor 2 in the Differentiation of Hair Follicle Stem Cells toward Endothelial Cells in a STAT5-dependent Manner 鹼性成纖維細胞生長因子2在毛囊幹細胞以STAT5依賴性方式向內皮細胞分化起了關鍵作用

Basic Fibroblast Growth Factor (Fgf2) Is Necessary for Cell Proliferation and Neurogenesis in the Developing Cerebral Cortex
鹼性成纖維細胞生長因子(Fgf2)對發育中的大腦皮層細胞增殖和神經發展是必需的因素

Basic Fibroblast Growth Factor Stimulates Corneal Endothelial Cell Growth and Endothelial Wound Healing of Human Corneas
鹼性成纖維細胞生長因子刺激人角膜的角膜內皮細胞生長和內皮傷口癒合

Bone Regeneration by Basic Fibroblast Growth Factor complexed with Biodegradable Hydrogels 鹼性成纖維細胞生長因子與可生物降解的水凝膠複合後的骨再生

Controlled Delivery of Basic Fibroblast Growth Factor Promotes Human Cardiosphere-Derived Cell Engraftment to Enhance Cardiac Repair for Chronic Myocardial Infarction 鹼性成纖維細胞生長因子的控制傳遞促進人類心球來源的細胞移植,以增強心臟修復慢性心肌梗死的能力

Increased Basic Fibroblast Growth Factor Expression Following Contusive Spinal Cord Injury
挫傷性脊髓損傷後的鹼性成纖維細胞生長因子增加

Priming with FGF2 Stimulates Human Dental Pulp Cells to Promote Axonal Regeneration and Locomotor Function Recovery after Spinal Cord Injury
用FGF2引發刺激人牙髓細胞,以促進脊髓損傷後軸突再生和運動功能的恢復

hEGF

The use of epidermal growth factor in dermatological practice  表皮生長因子在皮膚科實務中的應用

Epidermal Growth Factor as a Biologic Switch in Hair
表皮生長因子作為毛髮生長週期的生物開關

Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt_β-Catenin Signaling 
表皮生長因子透過 Wnt_β-Catenin 訊號促進毛囊外根鞘細胞的增殖和遷移

NMN

Effect of Oral Administration of Nicotinamide Mononucleotide on Clinical Parameters and Nicotinamide Metabolite Levels in Healthy Japanese Men
口服煙酰胺單核苷酸(NMN)對日本健康男性的臨床參數和煙酰胺代謝產物水平的影響

Nicotinamide Mononucleotide – A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD⁺ Metabolism 煙酰胺單核苷酸(NMN) – 一種靶向NAD⁺代謝的有望治療多種疾病的分子

Nicotinamide Mononucleotide – Exploration of Diverse Therapeutic Applications of a Potential Molecule
煙酰胺單核苷酸(NMN) – 潛在分子的多種治療應用的探索

Nicotinamide Mononucleotide (NMN) Supplementation Promotes Anti-Aging miRNA Expression Profile in the Aorta of Aged Mice,Predicting Epigenetic Rejuvenation and Anti-Atherogenic Effects
補充煙酰胺單核苷酸(NMN)可以促進衰老小鼠主動脈中的抗衰老miRNA表達譜,預測表觀遺傳的逆齡和抗動脈粥樣硬化的作用

SIRT2 Induces the Checkpoint Kinase BubR1 to Increase Lifespan
SIRT2誘導檢查點激酶BubR1延長壽命

The First Human Clinical Study for NMN has Started in Japan

NMN的第一項人體臨床研究已在日本啟動

Therapeutic Potential of NAD-Boosting Molecules : The In Vivo Evidence

NAD促進分子的治療潛力: 體內證據

槲皮素

Daily Quercetin Supplementation Dose-Dependently Increases Plasma Quercetin Concentrations in Healthy Humans

每天補充槲皮素劑量依賴性地增加健康人類的血漿槲皮素濃度

Health Effects of Quercetin: From Antioxidant to Nutraceutical
槲皮素對健康的影響: 從抗氧化劑到營養保健品

In Vivo Quercitrin Anti-Inflammatory Effect Involves Release of Quercetin, which Inhibits Inflammation through Down-Regulation of the NF-KappaB Pathway
體內槲皮素的抗炎作用涉及釋放槲皮素,槲皮素通過下調NF-κB途徑抑制炎症

Mechanisms of Neuroprotection by Quercetin : Counteracting Oxidative Stress and More
槲皮素的神經保護機制 – 抵抗氧化應激等等

Quercetin and Vitamin C: An Experimental, Synergistic Therapy for the Prevention and Treatment of SARS-CoV-2 Related Disease (COVID-19)
槲皮素和維生素C: 預防和治療SARS-CoV-2相關疾病 (COVID-19) 的實驗性協同療法

Quercetin Enhances Intestinal Barrier Function through the Assembly of Zonnula Occludens-2, Occludin, and Claudin-1 and the Expression of Claudin-4 in Caco-2 Cells
槲皮素通過Zonnula Occludens-2, Occludin和Claudin-1的組合以及Claudin-4在Caco-2細胞中的表達增強腸道屏障功能

Quercetin Increases Brain and Muscle Mitochondrial Biogenesis and Exercise Tolerance
槲皮素增強大腦和肌肉線粒體的生物發生和運動耐力

Quercetin, Cafeic Acid and Resveratrol Regulate Circadian Clock Genes and Aging‑Related Genes in Young and Old Human Lung Fbroblast Cells
槲皮素、咖啡酸和白藜蘆醇調節年輕人和老年人肺成纖維細胞中的晝夜節律基因和衰老相關基因

兒茶素

Catechin in Human Health and Disease

兒茶素在人類健康與疾病中的作用

Preparation of Catechin Extracts and Nanoemulsions from Green Tea Leaf Waste and their Inhibition Effect on Prostate Cancer Cell PC-3
綠茶渣中兒茶素提取物和納米乳的製備及其對前列腺癌細胞PC-3的抑製作用

Green Tea Catechins: Their Use in Treating and Preventing Infectious Diseases
綠茶兒茶素:它們在治療和預防傳染病中的用途

A Review of the Health Effects of Green Tea Catechins in In Vivo Animal Models
綠茶中的兒茶素對人體的健康效用

白藜蘆醇

Health Effects of Resveratrol : Results from Human Intervention Trials

白藜蘆醇對健康的影響: 人類干預試驗的結果

Indomethacin and Resveratrol as Potential Treatment Adjuncts for SARS-CoV-2_COVID-19
消炎痛和白藜蘆醇可作為SARS-CoV-2/COVID-19的潛在治療輔助劑

Multiplicity of Effects and Health Benefits of Resveratrol
白藜蘆醇的多種功效和健康益處

Quercetin, Cafeic Acid and Resveratrol Regulate Circadian Clock Genes and Aging‑Related Genes in Young and Old Human Lung Fbroblast Cells
槲皮素、咖啡酸和白藜蘆醇調節年輕人和老年人肺成纖維細胞中的晝夜節律基因和衰老相關基因

Resveratrol and health – A comprehensive review of human clinical trials
白藜蘆醇與健康-人體臨床試驗的全面回顧

Resveratrol as an Anti-Inflammatory and Anti-Aging Agent: Mechanisms and Clinical Implications
白藜蘆醇作為抗炎和抗衰老劑: 機制和臨床意義

Resveratrol Brain Delivery for Neurological Disorders Prevention and Treatment
白藜蘆醇的腦部遞送以預防和治療神經系統疾病

Role of Resveratrol in Regulating Cutaneous Functions
白藜蘆醇在調節皮膚功能中的作用

PQQ

Effect and mechanism of pyrroloquinoline quinone on anti-osteoporosis in Bmi-1 knockoutmice-Anti-oxidant effect of pyrroloquinoline quinone PQQ Bmi-1基因敲除小鼠骨質疏鬆的作用及機轉 – PQQ的抗氧化作用

Pyrroloquinoline quinone (PQQ) alleviated sepsis- induced acute liver injury, inflammation, oxidative stress and cell apoptosis by downregulating CUL3 expression
吡咯喹啉醌 (PQQ) 透過下調 CUL3 表達減輕敗血症引起的急性肝損傷、發炎、氧化壓力和細胞凋亡

Multiplicity of Effects and Health Benefits of Resveratrol
白藜蘆醇的多種功效和健康益處

Q10

Biochemical Functions of Coenzyme Q10

輔酶Q10的生物化學功能

Clinical aspects of coenzyme Q10: An update
輔酶 Q10在臨床方面的更新

Coenzyme Q10 in health and disease
輔酶 Q10 在健康與疾病中的作用Multiplicity of Effects and Health Benefits of Resveratrol
白藜蘆醇的多種功效和健康益處

Coenzyme Q10 Supplementation in Aging and Disease
輔酶 Q10 對抗老化和疾病的補充

Early Coenzyme Q10 Supplementation in Primary Coenzyme Q10 Deficiency
原發性輔酶 Q10 缺乏症的早期輔酶 Q10 補充

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